A comparative study of serum zinc levels in male hypertensive and non-hypertensive individuals in Peshawar Khyber Pakhtunkhwa, Pakistan

Abstract

Background: Numerous studies have shown that serum levels of trace elements including zinc play an essential role in regulation of hypertension. Objective: The objective of current study is to evaluate the differences in serum zinc levels among hypertensive and non-hypertensive male participants from Peshawar Khyber Pakhtun Khwa in Pakistan. Method: The study comprised of 140 adult males (70 hypertensive and 70 non-hypertensive). The subject’s age, weight, heights, and medical histories were acquired with informed consent on a well-designed proforma. Fresh blood samples were taken from 140 male participants in a Gel tube. The lipid profile test assessed total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein. An atomic absorption spectrophotometer with an acetylene flame was used for determination of serum zinc levels under normal conditions (Model Perkin Elmer AAS 700). Results: The mean serum zinc level (0.07115mg/dL) was lower in hypertensive subjects in comparison with non-hypertensive subjects (0.3428mg/dL).Conclusion: The mean serum zinc level in hypertensive subjects was lower than in non-hypertensive subjects.